TPPP protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TPPP

Tubulin polymerization promoting protein. (220 aa)

Predicted Functional Partners:

SNCG

0.830

GPNMB

0.657

ENSCAPP00000010142

0.629

CRYAB

0.616

DUSP13

0.583

ENSCAPP00000005281

0.578

SQSTM1

0.567

ENSCAPP00000001383

0.545

OAZ3

0.545

BTBD18

0.475

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTBD18	TPPP	ENSCAPP00000009376	ENSCAPP00000006269	BTB domain containing 18.	Tubulin polymerization promoting protein.	0.475
CRYAB	ENSCAPP00000010142	ENSCAPP00000006333	ENSCAPP00000010142	Crystallin alpha B.	annotation not available	0.604
CRYAB	GPNMB	ENSCAPP00000006333	ENSCAPP00000006512	Crystallin alpha B.	Glycoprotein nmb.	0.435
CRYAB	SNCG	ENSCAPP00000006333	ENSCAPP00000007204	Crystallin alpha B.	Synuclein gamma.	0.834
CRYAB	TPPP	ENSCAPP00000006333	ENSCAPP00000006269	Crystallin alpha B.	Tubulin polymerization promoting protein.	0.616
DUSP13	OAZ3	ENSCAPP00000011259	ENSCAPP00000017628	Dual specificity phosphatase 13.	Ornithine decarboxylase antizyme 3.	0.538
DUSP13	TPPP	ENSCAPP00000011259	ENSCAPP00000006269	Dual specificity phosphatase 13.	Tubulin polymerization promoting protein.	0.583
ENSCAPP00000001383	TPPP	ENSCAPP00000001383	ENSCAPP00000006269	annotation not available	Tubulin polymerization promoting protein.	0.545
ENSCAPP00000005281	TPPP	ENSCAPP00000005281	ENSCAPP00000006269	annotation not available	Tubulin polymerization promoting protein.	0.578
ENSCAPP00000010142	CRYAB	ENSCAPP00000010142	ENSCAPP00000006333	annotation not available	Crystallin alpha B.	0.604
ENSCAPP00000010142	GPNMB	ENSCAPP00000010142	ENSCAPP00000006512	annotation not available	Glycoprotein nmb.	0.541
ENSCAPP00000010142	SNCG	ENSCAPP00000010142	ENSCAPP00000007204	annotation not available	Synuclein gamma.	0.417
ENSCAPP00000010142	SQSTM1	ENSCAPP00000010142	ENSCAPP00000012680	annotation not available	Sequestosome 1.	0.998
ENSCAPP00000010142	TPPP	ENSCAPP00000010142	ENSCAPP00000006269	annotation not available	Tubulin polymerization promoting protein.	0.629
GPNMB	CRYAB	ENSCAPP00000006512	ENSCAPP00000006333	Glycoprotein nmb.	Crystallin alpha B.	0.435
GPNMB	ENSCAPP00000010142	ENSCAPP00000006512	ENSCAPP00000010142	Glycoprotein nmb.	annotation not available	0.541
GPNMB	SQSTM1	ENSCAPP00000006512	ENSCAPP00000012680	Glycoprotein nmb.	Sequestosome 1.	0.435
GPNMB	TPPP	ENSCAPP00000006512	ENSCAPP00000006269	Glycoprotein nmb.	Tubulin polymerization promoting protein.	0.657
OAZ3	DUSP13	ENSCAPP00000017628	ENSCAPP00000011259	Ornithine decarboxylase antizyme 3.	Dual specificity phosphatase 13.	0.538
OAZ3	TPPP	ENSCAPP00000017628	ENSCAPP00000006269	Ornithine decarboxylase antizyme 3.	Tubulin polymerization promoting protein.	0.545