Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEC11CSEC11 homolog C, signal peptidase complex subunit. (184 aa)    
Predicted Functional Partners:
SPCS2
Signal peptidase complex subunit 2.
   
 0.997
SPCS3
Signal peptidase complex subunit 3.
   
 0.995
IMMP1L
Inner mitochondrial membrane peptidase subunit 1.
     
 0.946
ENSCAPP00000018588
annotation not available
     
 0.942
NMBR
Neuromedin B receptor.
    
 0.920
ENSCAPP00000017675
annotation not available
     
 0.912
IMMP2L
Inner mitochondrial membrane peptidase subunit 2.
     
 0.908
PLAU
Plasminogen activator, urokinase.
     
  0.879
ALPL
Alkaline phosphatase, biomineralization associated.
    
 
 0.845
ENSCAPP00000000830
annotation not available
   
 
  0.788
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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