close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L2Mitotic arrest deficient 2 like 2. (158 aa)    
Predicted Functional Partners:
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
    
 0.999
BARD1
BRCA1 associated RING domain 1.
    
 0.998
POLD2
DNA polymerase delta 2, accessory subunit.
    
 0.997
REV1
REV1 DNA directed polymerase.
   
 0.995
POLD1
DNA polymerase delta 1, catalytic subunit.
    
 0.993
POLE
DNA polymerase epsilon, catalytic subunit.
    
 0.992
RAD51
RAD51 recombinase.
    
 0.982
ENSCAPP00000014704
annotation not available
   
 0.980
SHLD2
Shieldin complex subunit 2.
    
 
 0.969
CDC20
Cell division cycle 20.
    
 0.965
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (22%) [HD]