Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SHPRHSNF2 histone linker PHD RING helicase. (1593 aa)    
Predicted Functional Partners:
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.987
PCNA
Proliferating cell nuclear antigen.
   
 0.983
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
    
 0.894
ENSCAPP00000001550
annotation not available
    
 0.875
HLTF
Helicase like transcription factor.
   
 
 0.845
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.828
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 
 0.799
UBE2B
Ubiquitin conjugating enzyme E2 B.
    
 0.765
RECQL4
RecQ like helicase 4.
  
 
 0.744
PGM2
Phosphoglucomutase 2.
  
    0.726
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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