Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXO43F-box protein 43. (622 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle 20.
  
 0.995
CDC27
Cell division cycle 27.
   
 0.995
PLK1
Polo like kinase 1.
   
 0.994
ANAPC2
Anaphase promoting complex subunit 2.
    
 0.975
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
    
 0.968
SKP1
S-phase kinase associated protein 1.
    
 0.960
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.959
PLK3
Polo like kinase 3.
   
 0.957
CDK1
Cyclin dependent kinase 1.
   
 0.948
CUL1
Cullin 1.
    
 0.941
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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