Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PACC1Proton activated chloride channel 1. (344 aa)    
Predicted Functional Partners:
JADE1
Jade family PHD finger 1.
      
 0.667
CYB5D2
Cytochrome b5 domain containing 2.
      
 0.664
ENSCAPP00000016378
annotation not available
      
 0.641
TMEM160
Transmembrane protein 160.
      
 0.632
ENSCAPP00000010468
annotation not available
      
 0.598
MFN2
Mitofusin 2.
      
 0.579
TMEM171
Transmembrane protein 171.
      
 0.578
GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial.
    
 
 0.574
GOT1
Glutamic-oxaloacetic transaminase 1.
      
 0.568
ENSCAPP00000002629
annotation not available
      
 0.539
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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