RASGEF1B protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RASGEF1B

RasGEF domain family member 1B. (455 aa)

Predicted Functional Partners:

UNC5D

0.633

DLL1

0.629

CUX2

0.590

ENSCAPP00000007529

0.550

SOS1

0.515

ENSCAPP00000001610

0.511

ENSCAPP00000008539

0.511

ENSCAPP00000014369

0.511

ENSCAPP00000017895

0.511

ENSCAPP00000010613

0.495

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUX2	DLL1	ENSCAPP00000017727	ENSCAPP00000006759	Cut like homeobox 2.	Delta like canonical Notch ligand 1.	0.620
CUX2	RASGEF1B	ENSCAPP00000017727	ENSCAPP00000006372	Cut like homeobox 2.	RasGEF domain family member 1B.	0.590
CUX2	UNC5D	ENSCAPP00000017727	ENSCAPP00000003688	Cut like homeobox 2.	Unc-5 netrin receptor D.	0.578
DLL1	CUX2	ENSCAPP00000006759	ENSCAPP00000017727	Delta like canonical Notch ligand 1.	Cut like homeobox 2.	0.620
DLL1	RASGEF1B	ENSCAPP00000006759	ENSCAPP00000006372	Delta like canonical Notch ligand 1.	RasGEF domain family member 1B.	0.629
DLL1	UNC5D	ENSCAPP00000006759	ENSCAPP00000003688	Delta like canonical Notch ligand 1.	Unc-5 netrin receptor D.	0.633
ENSCAPP00000001610	ENSCAPP00000010613	ENSCAPP00000001610	ENSCAPP00000010613	annotation not available	annotation not available	0.583
ENSCAPP00000001610	RASGEF1B	ENSCAPP00000001610	ENSCAPP00000006372	annotation not available	RasGEF domain family member 1B.	0.511
ENSCAPP00000001610	SOS1	ENSCAPP00000001610	ENSCAPP00000002296	annotation not available	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.496
ENSCAPP00000007529	RASGEF1B	ENSCAPP00000007529	ENSCAPP00000006372	annotation not available	RasGEF domain family member 1B.	0.550
ENSCAPP00000008539	ENSCAPP00000010613	ENSCAPP00000008539	ENSCAPP00000010613	annotation not available	annotation not available	0.584
ENSCAPP00000008539	RASGEF1B	ENSCAPP00000008539	ENSCAPP00000006372	annotation not available	RasGEF domain family member 1B.	0.511
ENSCAPP00000008539	SOS1	ENSCAPP00000008539	ENSCAPP00000002296	annotation not available	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.496
ENSCAPP00000010613	ENSCAPP00000001610	ENSCAPP00000010613	ENSCAPP00000001610	annotation not available	annotation not available	0.583
ENSCAPP00000010613	ENSCAPP00000008539	ENSCAPP00000010613	ENSCAPP00000008539	annotation not available	annotation not available	0.584
ENSCAPP00000010613	ENSCAPP00000014369	ENSCAPP00000010613	ENSCAPP00000014369	annotation not available	annotation not available	0.578
ENSCAPP00000010613	ENSCAPP00000017895	ENSCAPP00000010613	ENSCAPP00000017895	annotation not available	annotation not available	0.584
ENSCAPP00000010613	RASGEF1B	ENSCAPP00000010613	ENSCAPP00000006372	annotation not available	RasGEF domain family member 1B.	0.495
ENSCAPP00000010613	SOS1	ENSCAPP00000010613	ENSCAPP00000002296	annotation not available	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.496
ENSCAPP00000014369	ENSCAPP00000010613	ENSCAPP00000014369	ENSCAPP00000010613	annotation not available	annotation not available	0.578