Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASGEF1BRasGEF domain family member 1B. (455 aa)    
Predicted Functional Partners:
UNC5D
Unc-5 netrin receptor D.
      
 0.743
ENSCAPP00000007529
annotation not available
      
 0.739
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.689
DLL1
Delta like canonical Notch ligand 1.
      
 0.685
SLC26A3
Solute carrier family 26 member 3.
   
  
 0.674
LINGO1
Leucine rich repeat and Ig domain containing 1.
   
  
 0.633
RASA1
RAS p21 protein activator 1.
    
 
 0.615
GRB2
Growth factor receptor bound protein 2.
     
 0.602
CUX2
Cut like homeobox 2.
   
  
 0.592
ARHGAP12
Rho GTPase activating protein 12.
      
 0.571
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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