Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCY2CGuanylate cyclase 2C. (959 aa)    
Predicted Functional Partners:
GUCA2A
Guanylate cyclase activator 2A.
   
 0.999
GUCA2B
Guanylate cyclase activator 2B.
    
 0.995
PDE10A
Phosphodiesterase 10A.
    
 0.976
PDE1B
Phosphodiesterase 1B.
     
 0.971
ENSCAPP00000006162
annotation not available
     
 0.959
PDE6C
Phosphodiesterase 6C.
    
 0.953
PDE6B
Phosphodiesterase 6B.
    
 0.953
PDE6A
Phosphodiesterase 6A.
    
 0.953
PDE5A
Phosphodiesterase 5A.
    
 0.950
PDE1C
Phosphodiesterase 1C.
     
 0.948
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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