Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTNPleiotrophin. (140 aa)    
Predicted Functional Partners:
PTPRZ1
Protein tyrosine phosphatase receptor type Z1.
   
 0.994
ALK
ALK receptor tyrosine kinase.
    
 0.989
ENSCAPP00000011313
annotation not available
   
    0.965
ENSCAPP00000013914
annotation not available
    
 0.911
PTPN1
Protein tyrosine phosphatase non-receptor type 1.
   
 0.815
ROS1
ROS proto-oncogene 1, receptor tyrosine kinase.
    
 0.786
OGN
Osteoglycin.
   
 
 0.763
SDC3
Syndecan 3.
    
 
 0.744
ODF1
Outer dense fiber of sperm tails 1.
      
 0.737
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.691
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.