close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000006439annotation not available (193 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.998
ROCK1
Rho associated coiled-coil containing protein kinase 1.
   
 0.961
ITSN1
Intersectin 1.
    
 0.955
ENSCAPP00000013032
annotation not available
    
 0.955
ENSCAPP00000003816
annotation not available
    
 0.950
ARHGEF12
Rho guanine nucleotide exchange factor 12.
   
 0.949
PKN1
Protein kinase N1.
    
 0.947
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 0.947
ENSCAPP00000000853
annotation not available
   
 0.944
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2.
   
 0.943
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.