Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
INF2Inverted formin, FH2 and WH2 domain containing. (1188 aa)    
Predicted Functional Partners:
SPOP
Speckle type BTB/POZ protein.
    
 
 0.970
ACTG2
Actin gamma 2, smooth muscle.
    
 0.913
SPOPL
Speckle type BTB/POZ protein like.
    
 
 0.886
FMN1
Formin 1.
    
 0.885
NPHS2
NPHS2 stomatin family member, podocin.
    
 
 0.764
ENSCAPP00000014682
annotation not available
      
 0.747
PLCE1
Phospholipase C epsilon 1.
      
 0.740
TRPC6
Transient receptor potential cation channel subfamily C member 6.
      
 0.738
DIAPH3
Diaphanous related formin 3.
     
 0.724
ENSCAPP00000013531
annotation not available
     
 0.724
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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