PNP protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PNP

Purine nucleoside phosphorylase. (240 aa)

Predicted Functional Partners:

ADA

0.985

NMRK1

0.970

APRT

0.968

GDA

0.966

NAPRT

0.963

ADK

0.961

XDH

0.950

SARM1

0.934

DCK

0.933

NT5E

0.927

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	ADK	ENSCAPP00000015416	ENSCAPP00000003273	Adenosine deaminase.	Adenosine kinase.	0.990
ADA	APRT	ENSCAPP00000015416	ENSCAPP00000008600	Adenosine deaminase.	Adenine phosphoribosyltransferase.	0.984
ADA	DCK	ENSCAPP00000015416	ENSCAPP00000000590	Adenosine deaminase.	Deoxycytidine kinase.	0.934
ADA	GDA	ENSCAPP00000015416	ENSCAPP00000016164	Adenosine deaminase.	Guanine deaminase.	0.696
ADA	NT5E	ENSCAPP00000015416	ENSCAPP00000001824	Adenosine deaminase.	5'-nucleotidase ecto.	0.953
ADA	PNP	ENSCAPP00000015416	ENSCAPP00000006518	Adenosine deaminase.	Purine nucleoside phosphorylase.	0.985
ADA	XDH	ENSCAPP00000015416	ENSCAPP00000015471	Adenosine deaminase.	Xanthine dehydrogenase.	0.735
ADK	ADA	ENSCAPP00000003273	ENSCAPP00000015416	Adenosine kinase.	Adenosine deaminase.	0.990
ADK	APRT	ENSCAPP00000003273	ENSCAPP00000008600	Adenosine kinase.	Adenine phosphoribosyltransferase.	0.995
ADK	DCK	ENSCAPP00000003273	ENSCAPP00000000590	Adenosine kinase.	Deoxycytidine kinase.	0.472
ADK	NMRK1	ENSCAPP00000003273	ENSCAPP00000014871	Adenosine kinase.	Nicotinamide riboside kinase 1.	0.427
ADK	NT5E	ENSCAPP00000003273	ENSCAPP00000001824	Adenosine kinase.	5'-nucleotidase ecto.	0.951
ADK	PNP	ENSCAPP00000003273	ENSCAPP00000006518	Adenosine kinase.	Purine nucleoside phosphorylase.	0.961
APRT	ADA	ENSCAPP00000008600	ENSCAPP00000015416	Adenine phosphoribosyltransferase.	Adenosine deaminase.	0.984
APRT	ADK	ENSCAPP00000008600	ENSCAPP00000003273	Adenine phosphoribosyltransferase.	Adenosine kinase.	0.995
APRT	DCK	ENSCAPP00000008600	ENSCAPP00000000590	Adenine phosphoribosyltransferase.	Deoxycytidine kinase.	0.537
APRT	GDA	ENSCAPP00000008600	ENSCAPP00000016164	Adenine phosphoribosyltransferase.	Guanine deaminase.	0.757
APRT	NT5E	ENSCAPP00000008600	ENSCAPP00000001824	Adenine phosphoribosyltransferase.	5'-nucleotidase ecto.	0.948
APRT	PNP	ENSCAPP00000008600	ENSCAPP00000006518	Adenine phosphoribosyltransferase.	Purine nucleoside phosphorylase.	0.968
APRT	XDH	ENSCAPP00000008600	ENSCAPP00000015471	Adenine phosphoribosyltransferase.	Xanthine dehydrogenase.	0.919