Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000006541annotation not available (89 aa)    
Predicted Functional Partners:
ENSCAPP00000010453
annotation not available
    
 0.997
VRK1
VRK serine/threonine kinase 1.
    
 0.982
LMNA
Lamin A/C.
    
 0.964
ENSCAPP00000014504
annotation not available
    
 0.959
VRK2
VRK serine/threonine kinase 2.
    
 0.954
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.
    
 
 0.897
ANKLE2
Ankyrin repeat and LEM domain containing 2.
    
 0.879
ENSCAPP00000001423
annotation not available
    
 0.874
LMNB1
Lamin B1.
    
 0.874
ENSCAPP00000011676
annotation not available
    
 0.864
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]