Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMEMembrane metalloendopeptidase. (633 aa)    
Predicted Functional Partners:
IDE
Insulin degrading enzyme.
      
 0.949
ACE
Angiotensin I converting enzyme.
     
 0.940
ENSCAPP00000000088
annotation not available
     
 0.933
ENSCAPP00000007791
annotation not available
     
 0.927
MEP1B
Meprin A subunit beta.
     
 0.917
ENSCAPP00000004293
annotation not available
     
 0.917
XPNPEP2
X-prolyl aminopeptidase 2.
   
 
 0.915
CPA3
Carboxypeptidase A3.
    
 0.912
CTSA
Cathepsin A.
     
  0.911
DPP7
Dipeptidyl peptidase 7.
     
 0.862
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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