STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM65Tripartite motif containing 65. (370 aa)    
Predicted Functional Partners:
DDX58
DExD/H-box helicase 58.
   
 0.969
IFIH1
Interferon induced with helicase C domain 1.
   
 0.955
TP53
Tumor protein p53.
    
 0.921
MAVS
Mitochondrial antiviral signaling protein.
    
 0.734
UBE2L6
Ubiquitin conjugating enzyme E2 L6.
    
 0.714
SQSTM1
Sequestosome 1.
    
 0.706
G3BP2
G3BP stress granule assembly factor 2.
    
 
 0.667
G3BP1
G3BP stress granule assembly factor 1.
    
 
 0.644
ICOS
Inducible T cell costimulator.
    
 0.643
DHX58
DExH-box helicase 58.
    
 0.636
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.