Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
ADAP2ArfGAP with dual PH domains 2. (328 aa)    
Predicted Functional Partners:
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
    
 0.768
OMG
Oligodendrocyte myelin glycoprotein.
    
 
 0.686
KCTD10
Potassium channel tetramerization domain containing 10.
    
   0.638
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.631
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 0.631
CTTN
Cortactin.
    
   0.621
ARFGAP3
ADP ribosylation factor GTPase activating protein 3.
    
 0.607
NCL
Nucleolin.
    
 
 0.593
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1.
    
 0.570
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2.
     
 0.564
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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