Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)    
Predicted Functional Partners:
ENSCAPP00000013033
annotation not available
    
 0.995
PBX2
PBX homeobox 2.
    
 0.984
ENSCAPP00000008781
annotation not available
    
 0.921
HMGB4
High mobility group box 4.
    
   0.897
ENSCAPP00000008431
annotation not available
   
   0.880
HMGB1
High mobility group box 1.
    
   0.640
ENSCAPP00000009768
annotation not available
    
   0.640
CCDC120
Coiled-coil domain containing 120.
    
   0.638
SMAD5
SMAD family member 5.
    
 0.596
ENSCAPP00000002730
annotation not available
    
 0.589
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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