Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AQP4Aquaporin 4. (326 aa)    
Predicted Functional Partners:
ENSCAPP00000004741
annotation not available
      
 0.919
GFAP
Glial fibrillary acidic protein.
   
  
 0.911
ENSCAPP00000005639
annotation not available
   
  
 0.816
ENSCAPP00000006780
annotation not available
  
  
0.769
ACE
Angiotensin I converting enzyme.
      
 0.746
AQP3
Aquaporin 3 (Gill blood group).
  
  
0.733
ENSCAPP00000017166
annotation not available
     
 0.725
ENSCAPP00000017181
annotation not available
  
 0.720
CFTR
CF transmembrane conductance regulator.
  
 
 0.719
SACM1L
SAC1 like phosphatidylinositide phosphatase.
      
 0.686
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.