Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF11TNF superfamily member 11. (259 aa)    
Predicted Functional Partners:
TNFRSF11A
TNF receptor superfamily member 11a.
    
 0.999
TNFRSF11B
TNF receptor superfamily member 11b.
    
 0.999
MITF
Melanocyte inducing transcription factor.
     
 0.931
ACP5
Acid phosphatase 5, tartrate resistant.
      
 0.879
TNFAIP6
TNF alpha induced protein 6.
    
 0.843
TNF
Tumor necrosis factor.
     
 0.828
TRAF6
TNF receptor associated factor 6.
    
 0.823
LTBR
Lymphotoxin beta receptor.
    
 0.804
NFATC1
Nuclear factor of activated T cells 1.
      
 0.785
CD40
CD40 molecule.
    
 0.773
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.