STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF5Interferon regulatory factor 5. (444 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor associated factor 6.
   
 0.973
ENSCAPP00000013460
annotation not available
     
 0.809
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.807
CREBBP
CREB binding protein.
    
 0.703
EP300
E1A binding protein p300.
    
 0.698
SGK3
Serum/glucocorticoid regulated kinase family member 3.
    
 0.677
STING1
Stimulator of interferon response cGAMP interactor 1.
   
 0.670
IRAK1
Interleukin 1 receptor associated kinase 1.
   
 0.630
SIRT5
Sirtuin 5.
    
 0.627
SIRT1
Sirtuin 1.
    
 0.627
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.