STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB7Growth factor receptor bound protein 7. (531 aa)    
Predicted Functional Partners:
ERBB2
Erb-b2 receptor tyrosine kinase 2.
   
 0.954
EGFR
Epidermal growth factor receptor.
   
 0.826
PDGFRB
Platelet derived growth factor receptor beta.
    
 0.823
ERBB3
Erb-b2 receptor tyrosine kinase 3.
   
 0.801
GRB2
Growth factor receptor bound protein 2.
    
 0.782
SHC1
SHC adaptor protein 1.
    
0.773
ENSCAPP00000013002
annotation not available
    
 0.753
MST1R
Macrophage stimulating 1 receptor.
   
 0.732
INSR
Insulin receptor.
    
 0.732
IGF1R
Insulin like growth factor 1 receptor.
    
 0.732
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.