node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ga0061063_0999 | Ga0061063_1000 | GCA_001418035_00792 | GCA_001418035_00793 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.773 |
Ga0061063_0999 | Ga0061063_1001 | GCA_001418035_00792 | GCA_001418035_00794 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein. | 0.727 |
Ga0061063_0999 | glyA | GCA_001418035_00792 | GCA_001418035_00790 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.549 |
Ga0061063_0999 | nrdR | GCA_001418035_00792 | GCA_001418035_00791 | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.917 |
Ga0061063_1000 | Ga0061063_0999 | GCA_001418035_00793 | GCA_001418035_00792 | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.773 |
Ga0061063_1000 | Ga0061063_1001 | GCA_001418035_00793 | GCA_001418035_00794 | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | Unannotated protein. | 0.727 |
Ga0061063_1000 | glyA | GCA_001418035_00793 | GCA_001418035_00790 | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.426 |
Ga0061063_1000 | nrdR | GCA_001418035_00793 | GCA_001418035_00791 | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.686 |
Ga0061063_1001 | Ga0061063_0999 | GCA_001418035_00794 | GCA_001418035_00792 | Unannotated protein. | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.727 |
Ga0061063_1001 | Ga0061063_1000 | GCA_001418035_00794 | GCA_001418035_00793 | Unannotated protein. | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.727 |
Ga0061063_1001 | glyA | GCA_001418035_00794 | GCA_001418035_00790 | Unannotated protein. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.404 |
Ga0061063_1001 | nrdR | GCA_001418035_00794 | GCA_001418035_00791 | Unannotated protein. | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.646 |
glyA | Ga0061063_0999 | GCA_001418035_00790 | GCA_001418035_00792 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.549 |
glyA | Ga0061063_1000 | GCA_001418035_00790 | GCA_001418035_00793 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.426 |
glyA | Ga0061063_1001 | GCA_001418035_00790 | GCA_001418035_00794 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein. | 0.404 |
glyA | nrdR | GCA_001418035_00790 | GCA_001418035_00791 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.580 |
nrdR | Ga0061063_0999 | GCA_001418035_00791 | GCA_001418035_00792 | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.917 |
nrdR | Ga0061063_1000 | GCA_001418035_00791 | GCA_001418035_00793 | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Unannotated protein; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.686 |
nrdR | Ga0061063_1001 | GCA_001418035_00791 | GCA_001418035_00794 | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Unannotated protein. | 0.646 |
nrdR | glyA | GCA_001418035_00791 | GCA_001418035_00790 | Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.580 |