node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFR47435.1 | SFR55403.1 | SAMN04488073_1820 | SAMN04488073_2748 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 0.976 |
SFR47435.1 | SFR60982.1 | SAMN04488073_1820 | SAMN04488073_3376 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Acetolactate synthase, small subunit. | 0.981 |
SFR47435.1 | SFR61709.1 | SAMN04488073_1820 | SAMN04488073_3466 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Oxaloacetate decarboxylase, alpha subunit. | 0.989 |
SFR47435.1 | ilvC | SAMN04488073_1820 | SAMN04488073_3377 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.603 |
SFR47435.1 | leuA | SAMN04488073_1820 | SAMN04488073_0608 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.961 |
SFR47435.1 | leuA-2 | SAMN04488073_1820 | SAMN04488073_2969 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.961 |
SFR47435.1 | leuB | SAMN04488073_1820 | SAMN04488073_0458 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.976 |
SFR47435.1 | leuC | SAMN04488073_1820 | SAMN04488073_0460 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.974 |
SFR47435.1 | leuD | SAMN04488073_1820 | SAMN04488073_0459 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.959 |
SFR55403.1 | SFR47435.1 | SAMN04488073_2748 | SAMN04488073_1820 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.976 |
SFR55403.1 | SFR60982.1 | SAMN04488073_2748 | SAMN04488073_3376 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | Acetolactate synthase, small subunit. | 0.993 |
SFR55403.1 | ilvC | SAMN04488073_2748 | SAMN04488073_3377 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.888 |
SFR55403.1 | leuA | SAMN04488073_2748 | SAMN04488073_0608 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.860 |
SFR55403.1 | leuA-2 | SAMN04488073_2748 | SAMN04488073_2969 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.843 |
SFR55403.1 | leuC | SAMN04488073_2748 | SAMN04488073_0460 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.997 |
SFR55403.1 | leuD | SAMN04488073_2748 | SAMN04488073_0459 | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.996 |
SFR60982.1 | SFR47435.1 | SAMN04488073_3376 | SAMN04488073_1820 | Acetolactate synthase, small subunit. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.981 |
SFR60982.1 | SFR55403.1 | SAMN04488073_3376 | SAMN04488073_2748 | Acetolactate synthase, small subunit. | Tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase. | 0.993 |
SFR60982.1 | SFR61709.1 | SAMN04488073_3376 | SAMN04488073_3466 | Acetolactate synthase, small subunit. | Oxaloacetate decarboxylase, alpha subunit. | 0.911 |
SFR60982.1 | ilvC | SAMN04488073_3376 | SAMN04488073_3377 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |