Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smurf1SMAD specific E3 ubiquitin protein ligase 1. (728 aa)    
Predicted Functional Partners:
smad7
SMAD family member 7.
    
 0.979
rps27a
Ribosomal protein S27a.
    
  0.976
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.972
ccm2
CCM2 scaffold protein.
    
 0.955
TGFBR2
TGF-beta receptor type-2-like.
    
 0.952
TGFBR2-2
TGF-beta receptor type-2-like.
    
 0.952
ptch1
Patched 1.
    
 0.951
ENSSORP00005038104
Patched 2.
    
 0.951
LOC115416245
TGF-beta receptor type-1-like.
    
 0.951
smad6
SMAD family member 6.
    
 0.949
Your Current Organism:
Sphaeramia orbicularis
NCBI taxonomy Id: 375764
Other names: S. orbicularis, orbiculate cardinalfish
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