STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSORP00005049319Vav 2 guanine nucleotide exchange factor. (845 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor bound protein 2.
    
0.918
LOC115433055
Lymphocyte cytosolic protein 2-like.
   
 0.886
LOC115417435
Tyrosine-protein kinase ZAP-70.
   
 0.852
syk
Spleen associated tyrosine kinase.
   
 0.852
ENSSORP00005050340
annotation not available
   
 
 0.845
LOC115416523
Phosphatidylinositol 3-kinase regulatory subunit alpha-like.
    
 
0.838
LOC115436749
Phosphatidylinositol 3-kinase regulatory subunit gamma-like.
    
 
0.834
ENSSORP00005051558
annotation not available
    
 
0.834
LOC115419450
Cell division control protein 42 homolog.
   
 0.823
CDC42
Cell division control protein 42 homolog.
   
 0.823
Your Current Organism:
Sphaeramia orbicularis
NCBI taxonomy Id: 375764
Other names: S. orbicularis, orbiculate cardinalfish
Server load: low (18%) [HD]