STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spo11SPO11 initiator of meiotic double stranded breaks. (389 aa)    
Predicted Functional Partners:
wdr61
WD repeat domain 61.
    
 
 0.949
ENSSORP00005016108
DNA topoisomerase II alpha.
    
 0.908
top2b
DNA topoisomerase II beta.
    
 0.908
ENSSORP00005026390
DNA meiotic recombinase 1.
    
 0.888
ENSSORP00005026404
DNA meiotic recombinase 1.
    
 0.888
rad50
RAD50 double strand break repair protein.
    
 0.872
ENSSORP00005006342
RAD51 paralog C.
    
 0.859
xrcc3
X-ray repair cross complementing 3.
    
 0.849
ENSSORP00005013424
RAD51 recombinase.
    
 0.842
ENSSORP00005013426
RAD51 recombinase.
    
 0.842
Your Current Organism:
Sphaeramia orbicularis
NCBI taxonomy Id: 375764
Other names: S. orbicularis, orbiculate cardinalfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.