| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0022 | murJ | BF49_0022 | BF49_0023 | FRUCTOKINASE EC 2714. | Proposed peptidoglycan lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.593 |
| BF49_0022 | trpS | BF49_0022 | BF49_0024 | FRUCTOKINASE EC 2714. | TryptophanyltRNA synthetase EC 6112; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.469 |
| BF49_5053 | mraY | BF49_5053 | BF49_5050 | Cell division protein FtsW; Belongs to the SEDS family. | PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.963 |
| BF49_5053 | murC | BF49_5053 | BF49_5055 | Cell division protein FtsW; Belongs to the SEDS family. | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | 0.977 |
| BF49_5053 | murG | BF49_5053 | BF49_5054 | Cell division protein FtsW; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.979 |
| BF49_5053 | murJ | BF49_5053 | BF49_0023 | Cell division protein FtsW; Belongs to the SEDS family. | Proposed peptidoglycan lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.648 |
| BF49_5053 | rpoD | BF49_5053 | BF49_2858 | Cell division protein FtsW; Belongs to the SEDS family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.626 |
| BF49_5053 | rpoH | BF49_5053 | BF49_2844 | Cell division protein FtsW; Belongs to the SEDS family. | RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.428 |
| BF49_5053 | yidC | BF49_5053 | BF49_3475 | Cell division protein FtsW; Belongs to the SEDS family. | Inner membrane protein translocase component YidC long form; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.592 |
| mraY | BF49_5053 | BF49_5050 | BF49_5053 | PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Cell division protein FtsW; Belongs to the SEDS family. | 0.963 |
| mraY | murC | BF49_5050 | BF49_5055 | PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | 0.964 |
| mraY | murG | BF49_5050 | BF49_5054 | PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.999 |
| mraY | murJ | BF49_5050 | BF49_0023 | PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Proposed peptidoglycan lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.437 |
| mraY | rpoD | BF49_5050 | BF49_2858 | PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.418 |
| murC | BF49_5053 | BF49_5055 | BF49_5053 | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | Cell division protein FtsW; Belongs to the SEDS family. | 0.977 |
| murC | mraY | BF49_5055 | BF49_5050 | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | PhosphoNacetylmuramoylpentapeptide transferase EC 27813; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.964 |
| murC | murG | BF49_5055 | BF49_5054 | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.984 |
| murC | murJ | BF49_5055 | BF49_0023 | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | Proposed peptidoglycan lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.483 |
| murC | rpoD | BF49_5055 | BF49_2858 | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.596 |
| murC | ruvC | BF49_5055 | BF49_4316 | UDPNacetylmuramatealanine ligase EC 6328; Cell wall formation; Belongs to the MurCDEF family. | Crossover junction endodeoxyribonuclease RuvC EC 31224; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.495 |