STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_0080Phosphopantothenoylcysteine decarboxylase EC 41136 Phosphopantothenoylcysteine synthetase EC 6325; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (488 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase EC 2773; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.996
dut
Deoxyuridine 5triphosphate nucleotidohydrolase EC 36123; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
  
 0.983
coaA
Pantothenate kinase EC 27133.
  
 
 0.978
panC
Pantoatebetaalanine ligase EC 6321; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.900
BF49_7015
Nucleoside triphosphate pyrophosphohydrolase MazG EC 3618.
     
  0.900
BF49_2942
Aspartate aminotransferase EC 2611.
 
  0.868
BF49_6845
Cysteine synthase EC 25147; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.823
BF49_0544
Cysteine synthase EC 25147.
    
 0.821
BF49_7059
Cysteine synthase B EC 25147.
    
 0.821
priA
Helicase PriA essential for oriCDnaAindependent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
    0.816
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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