STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BF49_0088FIG149041 Thioredoxin; Belongs to the thioredoxin family. (106 aa)    
Predicted Functional Partners:
BF49_2893
Thioredoxin reductase EC 1819.
 
 0.976
BF49_6388
Thioredoxin reductase EC 1819.
 
 
 0.796
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
 
  
 0.764
BF49_5758
Thioredoxin reductase EC 1819.
  
 
 0.757
BF49_4301
NADPHdependent glyceraldehyde3phosphate dehydrogenase EC 12113 NADdependent glyceraldehyde3phosphate dehydrogenase EC 12112; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.729
hslV
ATPdependent protease HslV EC 3425; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.698
BF49_3236
Thioredoxin reductase EC 1819.
 
 
 0.697
BF49_3402
Thioredoxin reductase EC 1819.
 
 
 0.697
fur
Ferric uptake regulation protein FUR; Belongs to the Fur family.
  
 
 0.691
BF49_7354
Ferric uptake regulation protein FUR.
  
 
 0.691
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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