Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
BF49_0090Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217. (246 aa)    
Predicted Functional Partners:
BF49_5964
Bll5683 probable serinethreonine phosphatase.
  
     0.699
BF49_0091
Dihydrofolate synthase EC 63212 Folylpolyglutamate synthase EC 63217; Belongs to the folylpolyglutamate synthase family.
       0.662
accD
Acetylcoenzyme A carboxyl transferase beta chain EC 6412; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
       0.645
BF49_4189
Hypothetical protein.
    
 0.632
BF49_6318
Alkyl hydroperoxide reductase subunit Clike protein.
   
 
 0.581
BF49_0169
Nucleoside 5triphosphatase RdgB dHAPTP dITP XTPspecific EC 36115; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.551
BF49_3435
Protein RcsF.
  
  
 0.551
trpA
Tryptophan synthase alpha chain EC 42120; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.454
BF49_5404
Sformylglutathione hydrolase EC 31212; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.448
trpB
Tryptophan synthase beta chain EC 42120; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.441
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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