STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpATryptophan synthase alpha chain EC 42120; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (278 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase beta chain EC 42120; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 0.999
trpC
Indole3glycerol phosphate synthase EC 41148; Belongs to the TrpC family.
 
 
 0.999
trpF
Phosphoribosylanthranilate isomerase EC 53124; Belongs to the TrpF family.
 
 0.998
trpD
Anthranilate phosphoribosyltransferase EC 24218; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.985
BF49_2303
Anthranilate synthase aminase component EC 41327 Anthranilate synthase amidotransferase component EC 41327.
 
 
 0.971
glyA
Serine hydroxymethyltransferase EC 2121; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.947
BF49_4185
Threonine dehydratase EC 43119.
  
 
 0.924
BF49_5172
Threonine dehydratase EC 43119.
  
 
 0.924
BF49_5743
Threonine dehydratase catabolic EC 43119.
  
 
 0.924
BF49_6805
Threonine dehydratase EC 43119.
  
 
 0.924
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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