| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0142 | BF49_0144 | BF49_0142 | BF49_0144 | Bsr0701 protein. | P-type Cu+ transporter; Lead cadmium zinc and mercury transporting ATPase EC 3633 EC 3635 Coppertranslocating Ptype ATPase EC 3634. | 0.711 |
| BF49_0142 | BF49_0145 | BF49_0142 | BF49_0145 | Bsr0701 protein. | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.416 |
| BF49_0144 | BF49_0142 | BF49_0144 | BF49_0142 | P-type Cu+ transporter; Lead cadmium zinc and mercury transporting ATPase EC 3633 EC 3635 Coppertranslocating Ptype ATPase EC 3634. | Bsr0701 protein. | 0.711 |
| BF49_0144 | BF49_0145 | BF49_0144 | BF49_0145 | P-type Cu+ transporter; Lead cadmium zinc and mercury transporting ATPase EC 3633 EC 3635 Coppertranslocating Ptype ATPase EC 3634. | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.568 |
| BF49_0145 | BF49_0142 | BF49_0145 | BF49_0142 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Bsr0701 protein. | 0.416 |
| BF49_0145 | BF49_0144 | BF49_0145 | BF49_0144 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | P-type Cu+ transporter; Lead cadmium zinc and mercury transporting ATPase EC 3633 EC 3635 Coppertranslocating Ptype ATPase EC 3634. | 0.568 |
| BF49_0145 | BF49_0599 | BF49_0145 | BF49_0599 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Hypothetical protein. | 0.862 |
| BF49_0145 | BF49_3591 | BF49_0145 | BF49_3591 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Hypothetical protein. | 0.862 |
| BF49_0145 | hfq | BF49_0145 | BF49_7017 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | RNAbinding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.493 |
| BF49_0145 | nnrE | BF49_0145 | BF49_6610 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | NADPHX epimerase NADPHX dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the rep [...] | 0.473 |
| BF49_0145 | ureG | BF49_0145 | BF49_4239 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.445 |
| BF49_0145 | zwf | BF49_0145 | BF49_4892 | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Glucose6phosphate 1dehydrogenase EC 11149; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.401 |
| BF49_0599 | BF49_0145 | BF49_0599 | BF49_0145 | Hypothetical protein. | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.862 |
| BF49_3591 | BF49_0145 | BF49_3591 | BF49_0145 | Hypothetical protein. | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.862 |
| hfq | BF49_0145 | BF49_7017 | BF49_0145 | RNAbinding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.493 |
| hfq | nnrE | BF49_7017 | BF49_6610 | RNAbinding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | NADPHX epimerase NADPHX dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the rep [...] | 0.418 |
| nnrE | BF49_0145 | BF49_6610 | BF49_0145 | NADPHX epimerase NADPHX dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the rep [...] | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.473 |
| nnrE | hfq | BF49_6610 | BF49_7017 | NADPHX epimerase NADPHX dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the rep [...] | RNAbinding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.418 |
| ureG | BF49_0145 | BF49_4239 | BF49_0145 | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.445 |
| zwf | BF49_0145 | BF49_4892 | BF49_0145 | Glucose6phosphate 1dehydrogenase EC 11149; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.401 |