Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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pyrFOrotidine 5phosphate decarboxylase EC 41123; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (236 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase EC 24210; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.999
pyrH
Uridine monophosphate kinase EC 27422; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.992
pyrD
Dihydroorotate dehydrogenase EC 1331; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.956
pyrB
Aspartate carbamoyltransferase EC 2132; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.956
upp
Uracil phosphoribosyltransferase EC 2429; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.935
upp-2
Uracil phosphoribosyltransferase EC 2429; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.935
carB
Carbamoylphosphate synthase large chain EC 6355; Belongs to the CarB family.
 
  
 0.929
surE
5nucleotidase SurE EC 3135; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.927
carA
Carbamoylphosphate synthase small chain EC 6355; Belongs to the CarA family.
  
  
 0.912
BF49_7015
Nucleoside triphosphate pyrophosphohydrolase MazG EC 3618.
  
  
  0.912
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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