Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_0208Protoporphyrinogen IX oxidase novel form HemJ EC 13. (125 aa)    
Predicted Functional Partners:
hemF
Coproporphyrinogen III oxidase aerobic EC 1333; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
  
 0.995
hemH
Ferrochelatase protoheme ferrolyase EC 49911; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.994
BF49_4445
Coproporphyrinogen III oxidase oxygenindependent EC 139922; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.936
hemE
Uroporphyrinogen III decarboxylase EC 41137; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.715
BF49_0206
FIG00441167 hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
     
 0.659
BF49_1435
CobN component of cobalt chelatase involved in B12 biosynthesis.
     
 0.640
BF49_0274
UroporphyrinogenIII synthase EC 42175; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
   
 0.604
dnaQ
DNA polymerase III epsilon subunit EC 2777; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
     0.577
BF49_2576
General secretion pathway protein O; Belongs to the peptidase A24 family.
   
    0.546
coaE
DephosphoCoA kinase EC 27124; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.545
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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