Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BF49_0389ABC transporter involved in cytochrome c biogenesis CcmB subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (222 aa)    
Predicted Functional Partners:
ccmC
Cytochrome ctype biogenesis protein CcmC putative heme lyase for CcmE; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmA
ABC transporter involved in cytochrome c biogenesis ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 0.999
ccmE
Cytochrome ctype biogenesis protein CcmE heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 0.992
BF49_0386
Cytochrome ctype biogenesis protein CcmGDsbE thioldisulfide oxidoreductase.
 
  
 0.952
BF49_1559
Cytochrome c heme lyase subunit CcmF.
 
  
 0.877
BF49_1558
Cytochrome c heme lyase subunit CcmL; Possible subunit of a heme lyase.
 
   
 0.852
BF49_1561
Cytochrome c heme lyase subunit CcmH.
 
   
 0.742
BF49_0387
Cytochrome ctype biogenesis protein CcmD interacts with CcmCE; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
     
 0.651
BF49_0119
ABC transporter ATPbinding protein.
     
 0.613
BF49_0964
FIG000906 Predicted Permease.
  
  
  0.608
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.