STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmAABC transporter involved in cytochrome c biogenesis ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (208 aa)    
Predicted Functional Partners:
BF49_0389
ABC transporter involved in cytochrome c biogenesis CcmB subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 0.999
ccmC
Cytochrome ctype biogenesis protein CcmC putative heme lyase for CcmE; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.995
ccmE
Cytochrome ctype biogenesis protein CcmE heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.845
BF49_1558
Cytochrome c heme lyase subunit CcmL; Possible subunit of a heme lyase.
 
   
 0.763
BF49_1559
Cytochrome c heme lyase subunit CcmF.
 
   
 0.743
lolD-2
Lipoprotein releasing system ATPbinding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
  
     0.710
BF49_0386
Cytochrome ctype biogenesis protein CcmGDsbE thioldisulfide oxidoreductase.
 
   
 0.667
rpsE
SSU ribosomal protein S5p S2e; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
     0.567
BF49_0391
Aconitate hydratase EC 4213; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
       0.543
BF49_1561
Cytochrome c heme lyase subunit CcmH.
 
   
 0.533
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.