| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0424 | BF49_0425 | BF49_0424 | BF49_0425 | Carboxylterminal protease EC 3421102; Belongs to the peptidase S41A family. | Periplasmic septal ring factor with murein hydrolase activity EnvCYibP. | 0.929 |
| BF49_0424 | nadD | BF49_0424 | BF49_0428 | Carboxylterminal protease EC 3421102; Belongs to the peptidase S41A family. | Nicotinatenucleotide adenylyltransferase EC 27718; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.407 |
| BF49_0424 | rlmH | BF49_0424 | BF49_0426 | Carboxylterminal protease EC 3421102; Belongs to the peptidase S41A family. | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.558 |
| BF49_0424 | rsfS | BF49_0424 | BF49_0427 | Carboxylterminal protease EC 3421102; Belongs to the peptidase S41A family. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.490 |
| BF49_0425 | BF49_0424 | BF49_0425 | BF49_0424 | Periplasmic septal ring factor with murein hydrolase activity EnvCYibP. | Carboxylterminal protease EC 3421102; Belongs to the peptidase S41A family. | 0.929 |
| BF49_0425 | rlmH | BF49_0425 | BF49_0426 | Periplasmic septal ring factor with murein hydrolase activity EnvCYibP. | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.564 |
| BF49_0425 | rsfS | BF49_0425 | BF49_0427 | Periplasmic septal ring factor with murein hydrolase activity EnvCYibP. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.441 |
| BF49_3027 | rlmH | BF49_3027 | BF49_0426 | 16S rRNA guanine966N2methyltransferase EC 211171. | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.610 |
| BF49_3027 | trmL | BF49_3027 | BF49_2308 | 16S rRNA guanine966N2methyltransferase EC 211171. | tRNA cytidine342Omethyltransferase EC 211207; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.426 |
| engB | rlmH | BF49_3476 | BF49_0426 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.631 |
| engB | rsfS | BF49_3476 | BF49_0427 | GTPbinding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.783 |
| nadD | BF49_0424 | BF49_0428 | BF49_0424 | Nicotinatenucleotide adenylyltransferase EC 27718; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Carboxylterminal protease EC 3421102; Belongs to the peptidase S41A family. | 0.407 |
| nadD | rlmH | BF49_0428 | BF49_0426 | Nicotinatenucleotide adenylyltransferase EC 27718; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.883 |
| nadD | rsfS | BF49_0428 | BF49_0427 | Nicotinatenucleotide adenylyltransferase EC 27718; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.964 |
| prmA | rlmH | BF49_5070 | BF49_0426 | Ribosomal protein L11 methyltransferase EC 211; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.646 |
| prmA | trmL | BF49_5070 | BF49_2308 | Ribosomal protein L11 methyltransferase EC 211; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | tRNA cytidine342Omethyltransferase EC 211207; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.406 |
| queE | rlmH | BF49_2309 | BF49_0426 | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.590 |
| queE | trmL | BF49_2309 | BF49_2308 | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | tRNA cytidine342Omethyltransferase EC 211207; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.768 |
| rlmH | BF49_0424 | BF49_0426 | BF49_0424 | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Carboxylterminal protease EC 3421102; Belongs to the peptidase S41A family. | 0.558 |
| rlmH | BF49_0425 | BF49_0426 | BF49_0425 | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Periplasmic septal ring factor with murein hydrolase activity EnvCYibP. | 0.564 |