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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proBGlutamate 5kinase EC 27211 RNAbinding Cterminal domain PUA; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa)    
Predicted Functional Partners:
proA
Gammaglutamyl phosphate reductase EC 12141; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
BF49_2793
Proline dehydrogenase EC 15998 Proline oxidase Delta1pyrroline5carboxylate dehydrogenase EC 15112; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.948
guaA
GMP synthase glutaminehydrolyzing EC 6352; Catalyzes the synthesis of GMP from XMP.
  
 
 0.940
BF49_1681
Acetylornithine aminotransferase EC 26111; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.939
pyrG
CTP synthase EC 6342; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
 0.931
carB
Carbamoylphosphate synthase large chain EC 6355; Belongs to the CarB family.
    
 0.925
BF49_3171
Glutamate synthase NADPH large chain EC 14113.
    
 0.924
hisF
Imidazole glycerol phosphate synthase cyclase subunit EC 413; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 
 0.912
carA
Carbamoylphosphate synthase small chain EC 6355; Belongs to the CarA family.
    
  0.907
proC
Pyrroline5carboxylate reductase EC 1512; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.862
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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