| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_2843 | obg | BF49_2843 | BF49_0433 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.933 |
| BF49_2843 | rplA | BF49_2843 | BF49_6214 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L1p L10Ae; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.505 |
| BF49_2843 | rplE | BF49_2843 | BF49_6242 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L5p L11e; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.855 |
| BF49_2843 | rplM | BF49_2843 | BF49_6600 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L13p L13Ae; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.830 |
| BF49_2843 | rplO | BF49_2843 | BF49_6249 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L15p L27Ae; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.891 |
| BF49_2843 | rplS | BF49_2843 | BF49_0371 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.844 |
| BF49_2843 | rplT | BF49_2843 | BF49_0134 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.867 |
| BF49_2843 | rplU | BF49_2843 | BF49_0439 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.780 |
| BF49_2843 | rpmA | BF49_2843 | BF49_0438 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L27p; Belongs to the bacterial ribosomal protein bL27 family. | 0.778 |
| BF49_2843 | rsfS | BF49_2843 | BF49_0427 | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.763 |
| obg | BF49_2843 | BF49_0433 | BF49_2843 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal large subunit pseudouridine synthase D EC 42170; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.933 |
| obg | rplA | BF49_0433 | BF49_6214 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L1p L10Ae; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.910 |
| obg | rplE | BF49_0433 | BF49_6242 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L5p L11e; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.873 |
| obg | rplM | BF49_0433 | BF49_6600 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L13p L13Ae; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.896 |
| obg | rplO | BF49_0433 | BF49_6249 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L15p L27Ae; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.897 |
| obg | rplS | BF49_0433 | BF49_0371 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.932 |
| obg | rplT | BF49_0433 | BF49_0134 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.965 |
| obg | rplU | BF49_0433 | BF49_0439 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.931 |
| obg | rpmA | BF49_0433 | BF49_0438 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | LSU ribosomal protein L27p; Belongs to the bacterial ribosomal protein bL27 family. | 0.951 |
| obg | rsfS | BF49_0433 | BF49_0427 | GTPbinding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.900 |
