Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
BF49_0473Serineglyoxylate aminotransferase EC 26145. (395 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase EC 2121; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.959
BF49_5168
Phosphoserine phosphatase EC 3133.
   
 0.955
gcvP
Glycine dehydrogenase decarboxylating glycine cleavage system P protein EC 1442; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 
 0.946
BF49_5939
Lallothreonine aldolase EC 2121.
    
 0.946
BF49_0069
Glyoxylate reductase EC 11179 Glyoxylate reductase EC 11126 Hydroxypyruvate reductase EC 11181; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.941
BF49_5886
Aminomethyltransferase glycine cleavage system T protein EC 21210.
  
 
 0.940
BF49_4361
D3phosphoglycerate dehydrogenase EC 11195.
  
 
 0.935
BF49_4940
D3phosphoglycerate dehydrogenase EC 11195.
  
 
 0.935
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 
 0.929
BF49_2933
Llactate dehydrogenase EC 1123.
  
 0.924
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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