Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmgAHomogentisate 12dioxygenase EC 113115; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (448 aa)    
Predicted Functional Partners:
BF49_0507
4hydroxyphenylpyruvate dioxygenase EC 1131127.
 
 0.999
BF49_3519
Maleylacetoacetate isomerase EC 5212 Glutathione Stransferase zeta EC 25118.
 
 
 0.999
BF49_0503
Fumarylacetoacetase EC 3712.
 
 
 0.988
BF49_0501
Metallobetalactamase family protein.
 
    0.919
BF49_2674
Conserved hypothetical protein.
  
 0.916
BF49_0499
Salicylate hydroxylase EC 114131.
 
  
 0.900
BF49_0500
Bsl0345 protein.
 
     0.866
BF49_0315
Pterin4alphacarbinolamine dehydratase EC 42196.
  
  
 0.747
BF49_0498
Transcriptional regulator MarR family.
 
   
 0.732
BF49_4863
Fumarylacetoacetase EC 3712.
  
 
 0.667
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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