| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF49_0619 | BF49_0620 | BF49_0619 | BF49_0620 | ATPDEPENDENT DNA HELICASE. | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | 0.809 |
| BF49_0619 | rplQ | BF49_0619 | BF49_6256 | ATPDEPENDENT DNA HELICASE. | LSU ribosomal protein L17p. | 0.636 |
| BF49_0620 | BF49_0619 | BF49_0620 | BF49_0619 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | ATPDEPENDENT DNA HELICASE. | 0.809 |
| BF49_0620 | BF49_6323 | BF49_0620 | BF49_6323 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | Macrolide export ATPbindingpermease protein MacB EC 363. | 0.766 |
| BF49_0620 | BF49_6536 | BF49_0620 | BF49_6536 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | Membrane protein putative. | 0.805 |
| BF49_0620 | grpE | BF49_0620 | BF49_0166 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.725 |
| BF49_0620 | hslU | BF49_0620 | BF49_0197 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | ATPdependent hsl protease ATPbinding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.767 |
| BF49_0620 | hslV | BF49_0620 | BF49_0194 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | ATPdependent protease HslV EC 3425; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.804 |
| BF49_0620 | rplQ | BF49_0620 | BF49_6256 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | LSU ribosomal protein L17p. | 0.777 |
| BF49_0620 | rplS | BF49_0620 | BF49_0371 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | LSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.828 |
| BF49_0620 | rpmB | BF49_0620 | BF49_0617 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | LSU ribosomal protein L28p; Belongs to the bacterial ribosomal protein bL28 family. | 0.738 |
| BF49_0620 | rpmH | BF49_0620 | BF49_3473 | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | LSU ribosomal protein L34p; Belongs to the bacterial ribosomal protein bL34 family. | 0.730 |
| BF49_6323 | BF49_0620 | BF49_6323 | BF49_0620 | Macrolide export ATPbindingpermease protein MacB EC 363. | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | 0.766 |
| BF49_6536 | BF49_0620 | BF49_6536 | BF49_0620 | Membrane protein putative. | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | 0.805 |
| grpE | BF49_0620 | BF49_0166 | BF49_0620 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | 0.725 |
| grpE | hslU | BF49_0166 | BF49_0197 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | ATPdependent hsl protease ATPbinding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.865 |
| grpE | hslV | BF49_0166 | BF49_0194 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | ATPdependent protease HslV EC 3425; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.863 |
| hslU | BF49_0620 | BF49_0197 | BF49_0620 | ATPdependent hsl protease ATPbinding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | Ribosomeassociated heat shock protein implicated in the recycling of the 50S subunit S4 paralog. | 0.767 |
| hslU | grpE | BF49_0197 | BF49_0166 | ATPdependent hsl protease ATPbinding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.865 |
| hslU | hslV | BF49_0197 | BF49_0194 | ATPdependent hsl protease ATPbinding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | ATPdependent protease HslV EC 3425; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.996 |
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