Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_06784hydroxythreonine4phosphate dehydrogenase EC 111262; Belongs to the PdxA family. (334 aa)    
Predicted Functional Partners:
BF49_2924
Phosphoserine aminotransferase EC 26152; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
     
 0.973
pdxJ
Pyridoxine 5phosphate synthase EC 26992; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
 
 
 0.929
pdxA
4hydroxythreonine4phosphate dehydrogenase EC 111262; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
  
  
 
0.919
BF49_2764
Threonine synthase EC 4231.
    
  0.903
BF49_4018
Threonine synthase EC 4231.
    
  0.903
BF49_6765
Threonine synthase EC 4231.
    
  0.903
BF49_0680
Tricarboxylate transport protein TctB.
 
     0.822
BF49_0679
Tricarboxylate transport membrane protein TctA.
 
     0.818
BF49_0681
Tricarboxylate transport protein TctC.
 
     0.617
BF49_1761
FIG00641944 hypothetical protein.
 
  
  0.549
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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