STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynATryptophan 23dioxygenase EC 1131111; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (279 aa)    
Predicted Functional Partners:
kynU
Kynureninase EC 3713; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 
 0.999
BF49_0902
Putative esterase.
 
 
 0.994
BF49_5786
Bll5848 putative decarboxylase.
     
 0.901
BF49_5575
Blr6059 putative cyclase.
  
 
 0.873
BF49_6487
Probable polyketide cyclase.
  
 
 0.857
trpA
Tryptophan synthase alpha chain EC 42120; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.821
trpB
Tryptophan synthase beta chain EC 42120; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.802
BF49_5553
AnthraniloylCoA monooxygenase EC 1141340.
 
  
 0.615
BF49_0507
4hydroxyphenylpyruvate dioxygenase EC 1131127.
 
  
 0.585
BF49_5558
Acetylcoenzyme A synthetase EC 6211.
 
  
 0.584
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.