close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdA35cyclicnucleotide phosphodiesterase EC 31417; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (283 aa)    
Predicted Functional Partners:
BF49_2788
Adenylate cyclase EC 4611.
  
  
 0.939
BF49_2092
Adenylate cyclase EC 4611 Guanylate cyclase EC 4612.
  
  
 0.929
BF49_3153
Adenylate cyclase EC 4611.
  
  
 0.927
BF49_2663
Adenylate cyclase EC 4611 Guanylate cyclase EC 4612.
  
  
 0.922
BF49_2665
Adenylate cyclase EC 4611.
  
  
 0.922
BF49_0270
Adenylate cyclase EC 4611 Guanylate cyclase EC 4612.
  
  
 0.921
BF49_6008
Adenylate cyclase EC 4611.
  
  
 0.919
BF49_6532
Adenylate cyclase EC 4611 Guanylate cyclase EC 4612.
  
  
 0.919
BF49_3089
Adenylate cyclase EC 4611.
  
  
 0.915
amn
AMP nucleosidase EC 3224; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
  
  
  0.911
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: low (32%) [HD]