Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdxA4hydroxythreonine4phosphate dehydrogenase EC 111262; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (338 aa)    
Predicted Functional Partners:
BF49_2924
Phosphoserine aminotransferase EC 26152; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
     
 0.990
pdxJ
Pyridoxine 5phosphate synthase EC 26992; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
 
 
 0.983
BF49_0678
4hydroxythreonine4phosphate dehydrogenase EC 111262; Belongs to the PdxA family.
  
  
 
0.919
BF49_2764
Threonine synthase EC 4231.
    
  0.903
BF49_4018
Threonine synthase EC 4231.
    
  0.903
BF49_6765
Threonine synthase EC 4231.
    
  0.903
rsmA
SSU rRNA adenine1518N6adenine1519N6 dimethyltransferase EC 211182; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.874
BF49_0966
Survival protein SurA precursor Peptidylprolyl cistrans isomerase SurA EC 5218.
  
  
 0.848
BF49_0969
Alcohol dehydrogenase.
       0.767
lptD
LPS-assembly protein LptD; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
  
 0.667
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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