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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase EC 2748; Essential for recycling GMP and indirectly, cGMP. (219 aa)    
Predicted Functional Partners:
guaA
GMP synthase glutaminehydrolyzing EC 6352; Catalyzes the synthesis of GMP from XMP.
 
 
 0.997
ndk
Nucleoside diphosphate kinase EC 2746; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.993
BF49_0774
Ribonucleotide reductase of class II coenzyme B12dependent EC 11741; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
 0.992
apt
Adenine phosphoribosyltransferase EC 2427; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.979
gpt
Xanthineguanine phosphoribosyltransferase EC 24222; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
  
 
 0.979
BF49_0297
GMP synthase glutaminehydrolyzing EC 6352.
  
 
 0.955
BF49_0979
Protein YicC.
  
  
 0.952
BF49_4234
Metal dependent phosphohydrolase.
  
 
 0.943
BF49_6511
GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.943
BF49_4394
Pyruvate kinase EC 27140; Belongs to the pyruvate kinase family.
 
 
 0.939
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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