STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derGTPbinding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (460 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase EC 27425.
 
 0.986
gpsA
Glycerol3phosphate dehydrogenase NADP EC 11194; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.945
BF49_3028
tRNA pseudouridine synthase A EC 42170; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.917
secA
Protein export cytoplasm protein SecA ATPase RNA helicase TC 3A511; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
 
  
 0.903
dnaG
DNA primase EC 277; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
 
  
 0.861
BF49_0307
GTPbinding protein TypABipA.
  
  
 0.845
pyrH
Uridine monophosphate kinase EC 27422; Catalyzes the reversible phosphorylation of UMP to UDP.
 
 
 0.843
BF49_5547
Opine dehydrogenase EC 15128; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.840
ffh
Signal recognition particle subunit Ffh SRP54 TC 3A511; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the [...]
 
  
 0.814
BF49_1013
Tetracyclineefflux transporter.
       0.801
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.