Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_1140Xylonate dehydratase EC 42182; Belongs to the IlvD/Edd family. (609 aa)    
Predicted Functional Partners:
ilvC
Ketolacid reductoisomerase EC 11186; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.935
BF49_2993
Branchedchain amino acid aminotransferase EC 26142.
  
 0.860
leuC
3isopropylmalate dehydratase large subunit EC 42133; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.828
BF49_5173
Acetolactate synthase small subunit EC 2216.
 
 
 0.826
leuA
2isopropylmalate synthase EC 23313; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.823
BF49_0550
Branchedchain amino acid aminotransferase EC 26142.
  
 0.804
BF49_1141
2keto3deoxyLfuconate dehydrogenase.
 
  
  0.747
BF49_5171
Acetolactate synthase large subunit EC 2216.
 
 
 0.739
BF49_3121
Dalanine aminotransferase EC 26121.
  
 0.738
BF49_6805
Threonine dehydratase EC 43119.
 
 
 0.717
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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