Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF49_13042hydroxy3oxopropionate reductase EC 11160. (290 aa)    
Predicted Functional Partners:
BF49_1098
Methylmalonatesemialdehyde dehydrogenase EC 12127.
 
 
 0.965
BF49_1272
Aldehyde dehydrogenase EC 1213; Belongs to the aldehyde dehydrogenase family.
  
 
 0.935
BF49_1867
Aldehyde dehydrogenase EC 1213.
  
 
 0.935
BF49_3132
Aldehyde dehydrogenase EC 1213; Belongs to the aldehyde dehydrogenase family.
  
 
 0.935
BF49_1095
3hydroxyisobutyrate dehydrogenase EC 11131; Belongs to the HIBADH-related family.
  
  
 
0.928
BF49_2707
Omegaamino acidpyruvate aminotransferase EC 26118; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.919
BF49_6363
Biotin carboxylase EC 63414 Biotin carboxyl carrier protein.
  
 
  0.823
acsA
Acetylcoenzyme A synthetase EC 6211; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.808
BF49_1094
Acetylcoenzyme A synthetase EC 6211.
  
 
 0.808
BF49_2879
Acetylcoenzyme A synthetase EC 6211.
  
 
 0.808
Your Current Organism:
Bradyrhizobium sp.
NCBI taxonomy Id: 376
Other names: B. sp.
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